Reinforced Stone can withstand a nuclear explosion, if you build a wall at least 3 blocks thick. It can also be used to craft the Reinforced Door.A crater caused by a nuclear explosion. The left half was protected with a 3x3 wall of Reinforced Stone.
It is the second most resistant material after bedrock with a blast resistance of 150. (In Vanilla Minecraft obsidian has a blast resistance of 6,000; however, obsidian was nerfed by Industrial Craft, lowering its blast resistance to 40)Reinforced Stone and Reinforced Glass being used in a Reactor Chamber.